These highlights do not include all the information needed to use LOSARTAN POTASSIUM TABLETS safely and effectively. See full prescribing information for LOSARTAN POTASSIUM TABLETS. LOSARTAN POTASSIUM tablets, for oral useRx Only Initial U.S. Approval: 1995

FULL PRESCRIBING INFORMATION: CONTENTS* WARNING: FETAL TOXICITY 1 INDICATIONS AND USAGE 1.1 Hypertension 1.2 Hypertensive Patients with Left Ventricular Hypertrophy 1.3 Nephropathy in Type 2 Diabetic Patients 2 DOSAGE AND ADMINISTRATION 2.1 Hypertension 2.2 Hypertensive Patients with Left Ventricular Hypertrophy 2.3 Nephropathy in Type 2 Diabetic Patients 2.4 Dosage Modifications in Patients with Hepatic Impairment 2.5 Preparation of Suspension (for 200 mL of a 2.5 mg/mL suspension) 3 DOSAGE FORMS AND STRENGTHS 4 CONTRAINDICATIONS 5 WARNINGS AND PRECAUTIONS 5.1 Fetal Toxicity 5.2 Hypotension in Volumeor Salt-Depleted Patients 5.3 Renal Function Deterioration 5.4 Hyperkalemia 6 ADVERSE REACTIONS 6.1 Clinical Trials Experience 6.2 Postmarketing Experience 7 DRUG INTERACTIONS 7.1 Agents Increasing Serum Potassium 7.2 Lithium 7.3 Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) Including Selective Cyclooxygenase2 Inhibitors (COX-2 Inhibitors) Treatment of hypertension, to lower blood pressure in adults and children greater than 6 years old. Lowering blood pressure reduces the risk of fatal and nonfatal cardiovascular events, primarily strokes and myocardial infarctions. (1.1) Reduction of the risk of stroke in patients with hypertension and left ventricular hypertrophy. There is evidence that this benefit does not apply to Black patients. (1.2) Treatment of diabetic nephropathy with an elevated serum creatinine and proteinuria in patients with type 2 diabetes and a history of hypertension. (1.3)